Does Trintellix cause sexual side effects?

By Sarah Bradley, Aug 19, 2024

According to Alex Dimitriu, MD, psychiatrist, sleep medicine specialist, and founder of Menlo Park Psychiatry & Sleep Medicine, certain antidepressants—particularly SSRIs, which affect your serotonin levels—can cause a decrease in sex drive because they block specific receptors in the brain that contribute to sexual arousal. Additionally, increasing serotonin levels with SSRIs can lower the amount of dopamine in your brain, the “feel-good” hormone tied to desire. “Very generally speaking, there is a balance in the brain between serotonin and dopamine, and for some people, increasing serotonin can lower dopamine,” Dr. Dimitriu says. “I often tell my patients that SSRIs dull the passions, bad and good.” 

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