The Relationship Between Caffeine and Sleep

By Lauren Panoff, Aug 23, 2024

Alex Dimitriu, M.D., double board-certified in Psychiatry and Sleep Medicine, tells Sleepopolis that caffeine is a blocker of adenosine — a substance that relaxes your blood vessels and affects your heart rhythm. “Adenosine builds up in the brain as we get through the day, and when levels are higher, we begin to feel tired and sleepy. [Caffeine blocks adenosine], which is the reason it makes us feel awake and alert,” he says.

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