What It’s Called When You Get Sick After Suddenly Stopping Your Antidepressants 

By Lauren Vinopal, May 4, 2022

People who take antidepressants will stop abruptly for many reasons, but psychiatrist Alex Dimitriu says it often has to do with the fact that antidepressants take weeks to work. “Because of this delayed feedback loop, it’s easy to not see the benefits or costs of starting or stopping treatments — it can sometimes take weeks to catch up with you,” he explains. “Certain psych meds, especially ones with a shorter half-life, can have quite significant discontinuation symptoms.” For instance, faster-acting medications like venlafaxine, or Effexor, should be tapered off more carefully. 

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