Shaquille O’Neal Shares How Zepbound Helped with Sleep Apnea and Weight Loss
By Cathy Cassata, Jun 10, 2026
Zepbound may help with moderate to severe OSA by addressing obesity, which plays a significant role in OSA, said Alex Dimitriu, MD, founder of Menlo Park Psychiatry & Sleep Medicine. “Excess weight, especially around the neck, can narrow the airway and increase the risk of collapse during sleep,” he told Healthline. “Clinical evidence suggests that weight loss is highly effective in reducing disease severity.” Losing 10% to 15% of body weight can reduce OSA severity by as much as 50% in people with moderate obesity, Dimitriu said.
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