Depression Treatment: When to Consider TMS or Ketamine for Partial Response

By Elizabeth Millard, Apr 3, 2026

“Unlike antidepressants that target serotonin and dopamine, ketamine increases synaptic plasticity, essentially helping the brain rewire and form new connections quickly,” says Alex Dimitriu, MD, a psychiatrist and founder of Menlo Park Psychiatry and Sleep Medicine in California, and a medical reviewer for Everyday Health. “When someone feels horrible or is not responding to antidepressants, this type of rewiring can be helpful.”

Click HERE for the full article.