Can you take trazodone and lorazepam together?

By Leandra Beabout, Jan 20, 2025

Alex Dimitriu, MD, a double-board-certified psychiatrist, sleep medicine physician, and founder of Menlo Park Psychiatry & Sleep Medicine, says that while there are no known interactions between lorazepam and trazodone, he considers it ideal to take one or the other—not both. He also says trazodone is usually preferred because it is “gentler” and safer for long-term use.

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