What’s the best antidepressant for me?

By Sarah Bradley,  Jan. 20, 2022

While any SSRI or SNRI can cause discontinuation syndrome, the SNRI Effexor (venlafaxine) can be one of the trickiest to wean off, says psychiatrist and sleep medicine specialist Alex Dimitriu, MD, founder of Menlo Park Psychiatry & Sleep Medicine. “Venlafaxine is an excellent medication, but missed doses can give people ‘brain zaps’ and quick feelings of vertigo, which I’ve called ‘vestibular jitters,’” Dr. Dimitriu explains. “These go away, fortunately, but it can make it hard to stop venlafaxine in particular.” 

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